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In Toxizittsstudien an Ratten (20 mg/kg intramuskulr) und Hunden (10 mg/kg intramuskulr) gab es keine Todesflle, keine Gewichtsvernderungen, keine aufflligen Verhaltensnderungen
My brother has been diagnosed with this mutation, along with CADASIL
With this in mind, we adapted an alternative approach to hydrophobize the surface of GSH-AuNCs that relies on the electrostatic interaction between hydrophobic cationic phase transfer agent (namely dodecylamine, DDA) and the negatively charged GSH-AuNCs
The resulting suppression of GPX4 creates a self-reinforcing cycle, accelerating ROS accumulation and lipid radical formation
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